
Q Since I cannot smell, food tastes bland and I have become more depressed. Is there a connection between smell disorders and depression?
A Yes, about 40 to 50% of patients with smell disorders also experience symptoms of depression or anxiety. Smell is directly connected to the amygdala and hippocampus, which process memory and emotion, so when smell declines, emotional responses and appetite can also become dulled. It is important to combine psychological support with smell recovery.
Detailed Answer
The connection between smell and emotion is neuroanatomically very deep. Unlike other senses, the olfactory nerve connects directly to the amygdala and hippocampus without passing through the thalamus, immediately affecting emotional processing and memory. When smell disappears, scent memories are severed, and the pleasure of food, social interaction, and feelings of nostalgia all become dulled together.
Studies show that the prevalence of depression in patients with smell disorders is more than about twice that of the general population, and it is especially pronounced in post-COVID patients.
Korean Medicine Clinic Perspective
At Dongjedang, along with treating smell, we combine liver-soothing (sogan) and spirit-calming (anshin) prescriptions to lift a downcast mood. When appetite has declined, we also regulate the function of the spleen and stomach to induce recovery of overall condition. If there are severe depressive symptoms, we recommend referral to psychiatry.
Related FAQs
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Q
My smell disorder has lasted for two years. Is it worth starting treatment even now?
#Possibility / Realistic Goals
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Q
I heard that smell disorders can be an early sign of Parkinson's disease or dementia. Should I be worried?
#Comorbidities
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Q
I heard about something called olfactory training. How can I do it at home?
#Lifestyle Management
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Q
Please tell me about lifestyle habits that help with smell disorder recovery.
#Lifestyle Management
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Q
I heard that nasal bloodletting is also used for smell disorders. Is it safe? Are there any side effects?
#Safety
