Combining SSRIs (selective serotonin reuptake inhibitors), commonly used to treat intermittent explosive disorder, with herbal medicine is generally safe, but there are points to be aware of. Some herbal constituents can affect the blood concentration of SSRIs through liver metabolism. There is also a theoretical possibility of interaction when serotonin-active ingredients are taken simultaneously with SSRIs. Be sure to inform your prescribing Korean medicine doctor of all medications you are taking, and when necessary, manage your care safely through collaboration with your psychiatrist.