
Q What causes ADHD? Is it genetic?
A Genetic factors account for 70–80% of ADHD cases, with dopamine receptor gene variants being the primary cause.
Detailed Answer
The causes of ADHD are multifactorial, but genetic factors are the most significant at 70–80%. Variants in dopamine receptor genes (DRD4, DRD5) and the dopamine transporter gene (DAT1) are the most studied. Environmental factors such as prenatal exposure to tobacco smoke or alcohol, premature birth, and lead exposure can also contribute. Brain imaging studies show delayed development in the prefrontal cortex and basal ganglia.
Korean Medicine Clinic Perspective
In Korean medicine, a constitutionally weak Kidney Essence (선천지정) is associated with an ADHD predisposition. The innate constitution inherited from one's parents is compounded by postnatal factors such as diet, sleep, and stress, deepening Heart-Spleen Deficiency over time. At Dongjedang, we assess both constitution and organ function together to address both innate and acquired contributing factors.
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